Prof. Zhiguo Wang - Polypharmacology - Outstanding Scientist Award

Guangdong Provincial Key Laboratory for Mechanistic and Translational Research on Bidirectional Complications among Chronic Conditions, Jinan University, China - China

Author Profile

Early academic pursuits 🎓

Zhiguo Wang embarked on his academic journey with a strong foundation in pharmacology, pursuing his studies at Harbin Medical University in Heilongjiang, China. His early work laid the groundwork for a distinguished career focused on understanding chronic diseases and their complex interrelations. His rigorous training and commitment to research established him as a formidable scholar in the field of cardiovascular and chronic disease research.

Professional endeavors 🏢

Throughout his career, Zhiguo has held numerous prestigious positions, demonstrating his leadership in the medical and research communities. He is currently the Director and Professor at the Guangdong Provincial Key Laboratory for Mechanistic and Translational Research on Chronic Disease Complex Complications at Jinan University in Guangzhou, China. His role as a chief scientist and professor across various departments at the First Affiliated Hospital of Jinan University reflects his multifaceted expertise. Additionally, he has contributed significantly as a Distinguished Professor at Harbin Medical University and held a visiting professorship at the Montreal Heart Institute in Canada.

Contributions and research focus 🔬

Zhiguo's research focuses on the mechanistic and translational aspects of chronic diseases, particularly the bidirectional complications arising from these conditions. He has pioneered studies that explore the pathophysiology of cardiovascular diseases and their links to metabolic disorders. His work employs innovative Polypharmacology methodologies to investigate the underlying mechanisms of disease progression and to develop effective therapeutic strategies, aiming to improve patient outcomes in chronic disease management.

Accolades and recognition 🏅

Zhiguo Wang has received numerous accolades for his contributions to medical research, including being a Fellow of the American Heart Association (FAHA) and a Polypharmacology Fellow of the European Society of Cardiology (FESC). His recognition as a Marion L. Munro Research Scholar by the Canadian Diabetes Association further underscores his impactful research in chronic disease mechanisms. His extensive publication record in high-impact journals reflects his influence and standing in the academic community.

Impact and influence 🌍

Zhiguo's research has made a significant impact on the understanding of chronic diseases and their complications, influencing both clinical practice and public health strategies. His work is instrumental in bridging the gap between basic science and clinical applications, ultimately contributing to improved therapeutic approaches Polypharmacology for patients suffering from chronic conditions. He is a sought-after speaker and mentor, inspiring the next generation of researchers in his field.

Legacy and future contributions 🔮

As a leader in chronic disease research, Zhiguo Wang’s legacy is built on his commitment to advancing scientific knowledge and improving patient care. His ongoing research aims to unravel the complexities of chronic disease interactions and to foster innovative therapeutic strategies. With a focus on translational research, Zhiguo's future contributions are poised to drive significant advancements in understanding and treating chronic conditions, leaving a lasting impact on the field and enhancing healthcare outcomes globally.

Notable Publications

Topical GDF11 accelerates skin wound healing in both type 1 and 2 diabetic mouse models 2020(9)

Metformin Shortens Prolonged QT Interval in Diabetic Mice by Inhibiting L-Type Calcium Current 2020(8)

Fibroblast growth factor 21 inhibited ischemic arrhythmias via targeting miR-143/EGR1 axis 2020(38)

Increase of late sodium current contributes to enhanced susceptibility to atrial fibrillation in diabetic mice 2019(22)

Systematic analysis of intestinal microRNAs expression in HCC: Identification of suitable reference genes in fecal samples 2019(4)

🌱 Early academic pursuits

Ashima Bhaskar's journey into the world of science began with a strong academic foundation. she completed her bachelor's and master's degrees in zoology from delhi university, securing first division in both. her passion for research led her to pursue a phd at the school of life sciences, jawaharlal nehru university, where she focused on the "rescue of recombinant measles virus from cdna and studies on measles virus nucleoprotein." this early work laid the groundwork for her future contributions to immunology and virology.

🔬 Professional endeavors

Ashima has held several prominent positions in her career, showcasing her expertise in immunology and infectious diseases. she started as a research scientist at the immunology lab, icgeb, new delhi, and later served as a post-doctoral fellow at iisc, bangalore. her international experience includes a stint as a research scientist at epfl, lausanne, switzerland. she also held a dst-inspire faculty position at the national institute of immunology, new delhi, and currently serves as a dbt-iyba fellow at icgeb, new delhi, contributing significantly to the immunobiology group.

📚 Contributions and research focus

Ashima's research has primarily focused on understanding the complex mechanisms of immune responses, particularly in relation to Tuberculosis tuberculosis. her work has been instrumental in exploring the role of sirt2, a class iii hdac, in mycobacterial infection, and the epigenetic regulation of t cell responses during tuberculosis. she has successfully secured funding for several research projects from prestigious institutions like the department of science and technology (dst) and the department of biotechnology (dbt), india.

🏆 Accolades and recognition

Ashima's contributions to science have been widely recognized with numerous awards and honors. she was named women scientist of the year 2024 by the golden jubilee biotech park for women and received the serb women excellence award in 2022. her other notable accolades include the hgk-iyba 2020-21, insa medal for young scientist 2016, and multiple keystone symposia global health travel awards. these awards highlight Tuberculosis her outstanding contributions to the field of immunology and her dedication to advancing scientific knowledge.

🌍 Impact and influence

Ashima's research has had a significant impact on the understanding of immune responses to infectious diseases, particularly tuberculosis. her work on epigenetic mechanisms has provided new insights into the host immune responses to bcg vaccination, potentially influencing future vaccine strategies. as a mentor, she has also co-supervised phd students, helping shape the next generation of scientists. her international Tuberculosis collaborations and publications have further extended her influence in the global scientific community.

🔗 Legacy and future contributions

Ashima bhaskar's legacy in the field of immunology is marked by her pioneering research on epigenetic regulation and immune responses. as she continues her work at icgeb, new delhi, her future contributions are expected to further unravel the complexities of infectious diseases and immune mechanisms. her ongoing projects, including those funded by the department of biotechnology and the science and engineering research board, promise to yield new discoveries that could have far-reaching implications for public health.