Sarojini Naidu College for Women - India
AUTHOR PROFILE
ORCID
EARLY ACADEMIC PURSUITS 🎓
Jhuma Bhadra embarked on her academic journey with a keen interest in chemistry, which eventually led her to earn a Ph.D. in the subject. Her formative years were marked by rigorous academic training, setting a strong foundation in the fundamental and applied aspects of chemistry. Her early studies laid the groundwork for her future research endeavors in nucleolipid synthesis and antimicrobial therapeutics, areas that have profound implications in biomedical sciences.
PROFESSIONAL ENDEAVORS 💼
Jhuma’s professional career commenced with impactful postdoctoral fellowships at prestigious institutions like Boston College and Clemson University. At Boston College, she explored bacteriophage modification using Boron warheads, while her tenure at Clemson University focused on designing and synthesizing aminoglycoside and Hoechst-conjugated phosphorodiamidate morpholino oligomers (PMOs) to study their antibacterial activity. Her academic career progressed as she joined Kurseong College as an Assistant Professor, where she continued to contribute to the field of chemistry. She is currently an Assistant Professor at Sarojini Naidu College for Women, where she furthers her research and teaching responsibilities.
CONTRIBUTIONS AND RESEARCH FOCUS 🤞
Jhuma Bhadra’s research is centered around the synthesis and biomedical application of nucleolipids. Her notable work includes the design of novel aminoglycoside-nucleolipid conjugates aimed at developing potential antimicrobial therapeutics. Her research is not just confined to theoretical aspects but extends to practical applications that have the potential to combat Chemical Biology antibiotic resistance, a critical global health challenge. Her dedication to advancing the field is evident in her role as a supervisor to two Junior Research Fellows, guiding the next generation of researchers.
ACCOLADES AND RECOGNITION 🏆
Jhuma’s scholarly contributions have been recognized by the scientific community, notably through the receipt of a substantial grant from the Science and Engineering Research Board (SERB-DST) under the EMEQ scheme. The Rs. 48.9 lakh funding supports her groundbreaking project on antimicrobial therapeutics, underscoring the importance and potential impact of her work. Chemical Biology This recognition highlights her role as a leading researcher in her field.
IMPACT AND INFLUENCE 🌍
Jhuma Bhadra’s research impacts both the scientific community and broader society. Her work on nucleolipids and antimicrobial therapeutics addresses pressing health issues, contributing to the development of new strategies to combat bacterial infections. By integrating her research findings into her teaching, she influences and inspires her students, fostering a new wave of Chemical Biology scientific inquiry and innovation in chemistry.
LEGACY AND FUTURE CONTRIBUTIONS 💡
Jhuma’s legacy in the field of chemistry is characterized by her innovative approach to research and her commitment to education. As she continues her work at Sarojini Naidu College for Women, her contributions are poised to expand the frontiers of nucleolipid research and antimicrobial therapies. Her future endeavors will likely include further exploration of biomedical applications, continuing to bridge the gap between fundamental research and practical healthcare solutions. Jhuma Bhadra’s dedication ensures her lasting influence in the realm of chemical sciences and beyond.
NOTABLE PUBLICATIONS
- Title: Peptide Nucleic Acids: Recent Advancements and Future Opportunities in Biomedical Applications
Authors: Achinta Sannigrahi, Nayan De, Debmalya Bhunia, Jhuma Bhadra
Journal: Bioorganic Chemistry
DOI: 10.1016/j.bioorg.2025.108146
- Title: Understanding Antisense Oligonucleotide Efficiency in Inhibiting Prokaryotic Gene Expression
Authors: Sandra Story, Sayantan Bhaduri, Sudakshina Ganguly, Rambabu Dakarapu, Sarah L. Wicks, Jhuma Bhadra, Simeon Kwange, Dev Arya
Journal: ACS Infectious Diseases
DOI: 10.1021/acsinfecdis.3c00645
- Title: Self-Transfecting GMO-PMO Chimera Targeting Nanog Enable Gene Silencing In Vitro and Suppresses Tumor Growth in 4T1 Allografts in Mouse
Authors: Ujjal Das, Jayanta Kundu, Pallab Shaw, Chandra Bose, Atanu Ghosh, Shalini Gupta, Sudipta Sarkar, Jhuma Bhadra, Surajit Sinha
Journal: Molecular Therapy - Nucleic Acids
DOI: 10.1016/j.omtn.2023.03.011
- Title: Cananginone Abrogates EMT in Breast Cancer Cells through Hedgehog Signaling
Authors: Chandra Bose, Ujjal Das, Tapan Kumar Kuilya, Joyanta Mondal, Jhuma Bhadra, Priyanjalee Banerjee, Rajib Kumar Goswami, Surajit Sinha
Journal: Chemistry & Biodiversity
DOI: 10.1002/cbdv.202100823
- Title: Self-Transfecting GMO-PMO and PMO-GMO Chimeras Enable Gene Silencing In Vitro and In Vivo Zebrafish Model and NANOG Inhibition Induce the Apoptosis in Breast and Prostate Cancer Cells
Authors: Jayanta Kundu, Ujjal Das, Chandra Bose, Jhuma Bhadra, Surajit Sinha
Journal: Preprint
DOI: 10.1101/2021.06.04.447039