Dr. Mohadeseh Khoshandam - genetics - Best Researcher Award

Department of Reproductive Biology, Academic Center for Education, Culture and Research, Qom Branch, Qom - Iran

AUTHOR PROFILE

🌟 EARLY ACADEMIC PURSUITS

Mohadeseh Khoshandam embarked on her academic journey with a strong passion for molecular genetics. She earned her Bachelor's degree in Molecular Genetics from the Science and Arts University of Yazd in 2014, laying the foundation for her future endeavors. Her quest for advanced knowledge led her to pursue a Master’s degree in Cell and Molecular Biology at the National Institute of Genetic Engineering and Biotechnology (NIGEB) in Tehran, where she graduated in 2018. She further solidified her expertise by enrolling in a Ph.D. program in Molecular Genetics at NIGEB, where she successfully defended her dissertation in 2021.

🧬 PROFESSIONAL ENDEAVORS

As a dedicated educator and researcher, Mohadeseh has taken up multiple roles that highlight her expertise. She currently serves as a coach at the National Institute of Genetic Engineering and Biotechnology, contributing to scientific training and mentorship. Her teaching roles at Qom University and her involvement in workshops on bioinformatics and stem cell research reflect her commitment to education. She has also played an instrumental role in guiding participants in the Stem Cells and Regenerative Medicine Olympiad.

🔬 CONTRIBUTIONS AND RESEARCH FOCUS

Mohadeseh’s research portfolio reflects her innovative approach to addressing critical challenges in genetics and molecular biology. She has worked on developing gene-editing techniques genetics using CRISPR-Cas9 to combat diseases such as β-thalassemia, sickle cell anemia, and hemophilia A. Her research on pathological angiogenesis in breast cancer models and the use of peptide nanocarriers has opened new avenues in cancer therapy. She has also explored the role of nanotechnology in enhancing human sperm quality and improving semen parameters in clinical trials, showcasing her interdisciplinary research focus.

🏆 ACCOLADES AND RECOGNITION

Mohadeseh’s work has earned her recognition within the academic and research community. Her innovative projects, particularly in gene editing and regenerative medicine, have contributed genetics significantly to the advancement of molecular genetics. Her role as a coach and mentor highlights her influence in nurturing the next generation of scientists.

🌍 IMPACT AND INFLUENCE

Through her groundbreaking research and educational contributions, Mohadeseh has significantly impacted the fields of molecular genetics and regenerative medicine. Her work on CRISPR-Cas9 and nanotechnology applications in reproductive biology has paved the way for novel therapeutic interventions. Her teachings and workshops have inspired numerous students and genetics professionals, reinforcing her role as a transformative figure in her domain.

🔗 LEGACY AND FUTURE CONTRIBUTIONS

With her expertise in molecular genetics and dedication to education, Mohadeseh Khoshandam is poised to leave a lasting legacy in her field. Her pioneering work in gene editing and genetics nanotechnology holds promise for further advancements in genetic therapy and regenerative medicine. As she continues her journey, her commitment to innovation and mentorship ensures a bright future for the scientific community she serves.

NOTABLE PUBLICATIONS

Title: CRISPR, CAR-T, and NK: Current applications and future perspectives
Authors: Mohadeseh Khoshandam, Hossein Soltaninejad, Amir Ali Hamidieh, Saman Hosseinkhani
Journal: Genes & Diseases
Title: Clinical applications of the CRISPR/Cas9 genome-editing system: Delivery options and challenges in precision medicine
Authors: Mohadeseh Khoshandam, Hossein Soltaninejad, Marziyeh Mousazadeh, Amir Ali Hamidieh, Saman Hosseinkhani
Journal: Genes & Diseases
Title: Recent advances in developing 3D culture systems of spermatogonial stem cell preservation and differentiation: A narrative review
Authors: Leyla Fath-Bayati, Leila Naserpour, Mohadeseh Khoshandam, Rahil Jannatifar, Hoda Fazaeli
Journal: International Journal of Reproductive BioMedicine (IJRM)
Title: The role of MicroRNAs in female and male human reproduction: A Narrative Review
Authors: Mohadeseh Khoshandam, Leila Naserpour, Hossein Soltaninejad, Hadi Zare-Zardini, Ashraf Alsadat Hoseiny, Neda Golpar Raboki, Elahe Sadat Mousavi
Journal: Preprint
Title: CRISPR and Artificial intelligence to improve precision medicine: Future Perspectives and Potential Limitations
Authors: Mohadeseh Khoshandam, Hossein Soltaninejad, Amir Ali Hamidieh, Saman Hosseinkhani
Journal: Preprint

Early academic pursuits 🎓

Jerzy trojan completed his doctorate d’état ès sciences (hdr) at the prestigious sorbonne - p&m curie. during this formative period, he laid the groundwork for his future contributions to biomedical science, specifically in the field of cancerology. his early research endeavors, characterized by a rigorous scientific approach, focused on critical aspects of oncology and laid the foundation for his later groundbreaking work.

Professional endeavors 🏥

Jerzy has held various esteemed positions throughout his career, reflecting his commitment to advancing cancer research. he is currently a visiting professor at the insitm, cancer center, and paris-saclay university in villejuif, france, where he has been since 2019. before this, he served as president and research director at the international cancer gene therapy and oncology diagnostics center (ceadea) in bogota, colombia, and has also held prominent roles in institutions across the usa and europe, including case western reserve university and the sidney kimmel cancer center. these diverse experiences have equipped him with a comprehensive understanding of both the scientific and clinical aspects of cancer treatment.

Contributions and research focus 🔬

Dr. trojan is best known for establishing cancer gene therapy, particularly immuno-gene therapy, as a pivotal domain within oncology. his pioneering research, highlighted in publications from 1993, led to significant advancements in the treatment of glioblastoma, showcasing the therapeutic potential of gene therapy. Immuno - gene therapy additionally, he explored the intersection between neuro-ontogenesis and neuro-oncogenesis, identifying afp and igf-i as novel biomarkers, which have implications for understanding central nervous system differentiation and cancer progression.

Accolades and recognition 🏆

In recognition of his substantial contributions to biomedical science, jerzy was elected as a member of the prestigious french academy of medicine (anm) in paris in 2017. his extensive body of work includes nearly 370 publications, encompassing 140 articles, 102 book chapters, and four books, which have garnered over 3,500 Immuno - gene therapy citations. this impressive scholarly output underscores his impact and influence in the field of cancer research.

Impact and influence 🌍

Dr. trojan's research has significantly shaped the landscape of cancer therapy, particularly in immunotherapy. his establishment of immuno-gene therapy has opened new avenues for treating aggressive cancers, thus influencing both academic research and clinical practices. his work has not only contributed to theoretical Immuno - gene therapy advancements but has also informed practical applications that benefit patients facing challenging diagnoses.

Legacy and future contributions 🔮

With an enduring commitment to advancing cancer research, jerzy trojan continues to influence the field through his current role as a visiting professor and research director. his legacy is evident in the ongoing projects aimed at improving cancer treatment outcomes, particularly through innovative therapeutic strategies. as he continues to publish and mentor the next generation of researchers, his contributions will undoubtedly have a lasting impact on the future of oncology and gene therapy.

Notable Publications

Title: Precancerous Disease Systemic Lupus Erythematosus–The Role of BAFF in Corticosteroids Treatment
Author: J. Trojan et al.
Journal: Medical Research and Its Applications, Vol. 6, Pages 114-127
DOI: 10.9734/bpi/mria/v6/7520C
Publication Date: June 3, 2024

Title: Anti-Gene IGF-I Vaccines in Cancer Gene Therapy: A Review of a Case of Glioblastoma
Author: J. Trojan
Journal: Current Medicinal Chemistry, Vol. 31, Pages 1982-2002
DOI: 10.2174/0109298673231106095141
Publication Date: March 11, 2024

Title: Establishment of Cancer Gene Therapy
Author: J. Trojan
Journal: Cambridge Scholars Publishing
Publication Date: March 2, 2023

Title: Neoplastic brain, glioblastoma and immunotherapy
Author: J. Trojan et al.
Journal: In: Brain and Spinal Tumors - Primary and Secondary, Ed. L.R. Morgan, F.B. Sarica, InTechOpen
Publication Date: 2020

Title: In vitro technical aspects of Anti–Gene IGF-I vaccines against glioma
Author: J. Trojan et al.
Journal: IBR, Vol. 3(1), Pages 43-48
Publication Date: 2019