Yashraj Biotechnology - India
Author Profile
ORCID
🎓 Early academic pursuits
Dr. Amit Khanna's journey into the scientific world began with a strong foundation in bioinformatics and life sciences, complemented by a master's degree in technology (m.tech) and a doctorate (ph.d). his academic training fostered a deep understanding of cellular biology, molecular pharmacology, and translational research, setting the stage for his later work in drug discovery and disease modeling. with a growing interest in combining biological systems with advanced simulation tools, he also developed an appreciation for cross-disciplinary areas such as power electronics, where data integration and control systems play crucial roles.
💼 Professional endeavors
Dr. Khanna boasts more than 18 years of industrial research experience, working with prestigious organizations such as syngene international, piramal life sciences (plsl), strand life sciences, and yashraj biotechnology limited. currently, he serves as the head of integrated drug discovery & development at yashraj biotechnology limited, where he leads high-performing teams in the development of cutting-edge in vitro models. previously, he held leadership roles including senior director at intonation research laboratories and group lead at syngene international, overseeing complex biological projects and assay development.
🔬 Contributions and research focus
Dr. Khanna has significantly advanced the field of drug discovery, especially in the areas of cancer, neurodegenerative, cardiovascular, and inflammatory disorders. his work includes the iPSC - Stem cells development and validation of human-relevant disease models using stem cells (including ipsc), crispr-engineered cells, and advanced 2d/3d co-culture systems. he has also contributed to the standardization of biochemical and cell-based assays and led target engagement studies involving cetsa, protac, and nanobret technologies. through a data-driven and milestone-gated approach, he ensures regulatory compliance and research excellence. his analytical and scientific strategy often parallels principles found in power electronics, such as feedback control and system optimization.
🌍 Impact and influence
Dr. Khanna's leadership has enabled transformative research outcomes that align with industry benchmarks and regulatory standards. by fostering collaborations with cross-functional teams and outsourcing partners, he has significantly influenced the trajectory of drug discovery programs in india. his work has directly contributed to the identification and optimization of clinical iPSC - Stem cells candidates like the jak kinase inhibitor for pruritus. he has also led the development of 21 cfr part 11–compliant data strategies, shaping robust data governance within the discovery biology landscape. as integrated technologies continue to gain traction in biomedical research, his emphasis on data alignment mirrors the precision required in power electronics control frameworks.
📚 Academic cites
Dr. Khanna’s scientific contributions have been cited in multiple high-impact research studies, particularly in translational biology and pharmacological modeling. his publications, iPSC - Stem cells collaborations, and presentations at industry forums reflect his dedication to innovation and scientific communication. while specific citation metrics are not listed here, his impact is evident in the successful delivery of numerous discovery-phase projects and the clinical progression of lead compounds.
🧬 Legacy and future contributions
With a commitment to scientific rigor and innovation, dr. khanna continues to push the boundaries of drug discovery and translational research. his strategic vision includes expanding into organ-on-chip models, personalized therapy development, and high-throughput screening platforms. as technology and biology converge, his interdisciplinary mindset positions him to integrate fields like power electronics into next-generation biomedical solutions. his long-term legacy will be defined by the nurturing of scientific talent, enhancement of disease model accuracy, and promotion of global research collaborations.
Notable Publications
Title: Generation of human-induced pluripotent stem cell line from PBMC of healthy donor using integration-free Sendai virus technology
Author(s): Jaganmay Sarkar, Shreya Dhepe, Amrita Shivalkar, Rutuja Kuhikar, Shruti More, Vijay Bhaskar Reddy Konala, Paresh Bhanushali, Amit Khanna
Journal: Stem Cell Research