Dr. Hui Jia - Tumor chemotherapy resistance - Best Researcher Award
Shenyang Medical College - China
Author Profile
Early academic pursuits 📚
Dr. Hui Jia's journey in traditional chinese medicine began with a solid academic foundation. she earned her bachelor of pharmacy from shenyang pharmaceutical university, which sparked her interest in natural medicine and pharmacology. pursuing further studies, she obtained a master’s degree in traditional chinese medicine from shaanxi university of traditional chinese medicine. in 2021, she completed her ph.d. in traditional chinese medicine from shenyang pharmaceutical university, where her research honed in on the bioactive compounds of medicinal herbs and their therapeutic potential.
Professional endeavors 🏛️
Dr. Jia is currently an associate professor at the school of traditional chinese medicine, shenyang medical college. she has played a key role in shaping the institution’s research focus on herbal medicines and natural products. her dedication to teaching and mentorship is evident, as she actively guides students in exploring the intricate mechanisms of traditional remedies, while leading significant research projects that address major health challenges like drug-resistant cancers.
Contributions and research focus 🔬
Dr. Hui jia’s primary research revolves around understanding the active ingredients of herbs and their molecular mechanisms, particularly in reversing drug Tumor chemotherapy resistance resistance. her work is centered on investigating the key protein targets of natural products. one of her significant contributions is her research on cimigenoside, a bioactive compound from cohosh, and its role in combating drug resistance in triple-negative breast cancer through the γ-secretase/nicd/notch-pxr axis. her innovative approach offers new insights into cancer treatment.
Accolades and recognition 🏅
Through her groundbreaking research, dr. jia has gained recognition in the scientific community. she has secured prestigious grants from both the national natural science foundation of china and liaoning province for her work on cancer drug resistance. her research projects reflect her excellence and leadership in the field of Tumor chemotherapy resistance traditional chinese medicine, addressing complex challenges in cancer treatment and advancing the potential of natural products as therapeutic agents.
Impact and influence 🌍
Dr. jia's research has far-reaching implications, particularly in the realm of cancer therapeutics. her work on γ-secretase inhibitors and their role in reversing drug resistance in triple-negative breast cancer highlights the importance of integrating traditional medicine with modern science. her studies provide new avenues for Tumor chemotherapy resistance treating difficult cancers, potentially transforming how drug resistance is managed in clinical settings.
Legacy and future contributions 🔮
with her deep-rooted passion for traditional chinese medicine, dr. hui jia is set to leave a lasting legacy in the field. her future contributions are expected to further bridge the gap between traditional herbal medicine and contemporary drug discovery. as she continues to explore the bioactive compounds of natural products and their mechanisms of action, her work will undoubtedly influence future generations of researchers and contribute to innovative cancer therapies.
Notable Publications
- Atorvastatin ameliorates diabetic nephropathy through inhibiting oxidative stress and ferroptosis signaling
Authors: Zhang, Y., Qu, Y., Cai, R., Ren, F., Zhou, M.-S.
Journal: European Journal of Pharmacology, 2024, 976, 176699 - Inhibition of γ-secretase/Notch pathway as a potential therapy for reversing cancer drug resistance
Authors: Feng, M., Santhanam, R.K., Xing, H., Zhou, M., Jia, H.
Journal: Biochemical Pharmacology, 2024, 220, 115991 - The role of angiotensin II activation of yes-associated protein/PDZ-binding motif signaling in hypertensive cardiac and vascular remodeling
Authors: Xu, Q., Zhuo, K., Zhang, X., Dong, J., Zhou, M.-S.
Journal: European Journal of Pharmacology, 2024, 962, 176252 - Cardiac macrophages in maintaining heart homeostasis and regulating ventricular remodeling of heart diseases
Authors: Kang, M., Jia, H., Feng, M., Zhang, L., Zhou, M.-S.
Journal: Frontiers in Immunology, 2024, 15, 1467089 - Cigarette smoke-induced exosomal miR-221-3p facilitates M1 macrophage polarization via the STAT3 pathway in chronic obstructive pulmonary disease
Authors: Jia, H., He, W., Wu, B., Wang, M., Xia, S.
Journal: Aging, 2024, 16(17), pp. 12379–12391