Dr. Jhuma Bhadra - Chemical Biology - Best Researcher Award

Sarojini Naidu College for Women - India

AUTHOR PROFILE

EARLY ACADEMIC PURSUITS 🎓

Jhuma Bhadra embarked on her academic journey with a keen interest in chemistry, which eventually led her to earn a Ph.D. in the subject. Her formative years were marked by rigorous academic training, setting a strong foundation in the fundamental and applied aspects of chemistry. Her early studies laid the groundwork for her future research endeavors in nucleolipid synthesis and antimicrobial therapeutics, areas that have profound implications in biomedical sciences.

PROFESSIONAL ENDEAVORS 💼

Jhuma’s professional career commenced with impactful postdoctoral fellowships at prestigious institutions like Boston College and Clemson University. At Boston College, she explored bacteriophage modification using Boron warheads, while her tenure at Clemson University focused on designing and synthesizing aminoglycoside and Hoechst-conjugated phosphorodiamidate morpholino oligomers (PMOs) to study their antibacterial activity. Her academic career progressed as she joined Kurseong College as an Assistant Professor, where she continued to contribute to the field of chemistry. She is currently an Assistant Professor at Sarojini Naidu College for Women, where she furthers her research and teaching responsibilities.

CONTRIBUTIONS AND RESEARCH FOCUS 🤞

Jhuma Bhadra’s research is centered around the synthesis and biomedical application of nucleolipids. Her notable work includes the design of novel aminoglycoside-nucleolipid conjugates aimed at developing potential antimicrobial therapeutics. Her research is not just confined to theoretical aspects but extends to practical applications that have the potential to combat Chemical Biology antibiotic resistance, a critical global health challenge. Her dedication to advancing the field is evident in her role as a supervisor to two Junior Research Fellows, guiding the next generation of researchers.

ACCOLADES AND RECOGNITION 🏆

Jhuma’s scholarly contributions have been recognized by the scientific community, notably through the receipt of a substantial grant from the Science and Engineering Research Board (SERB-DST) under the EMEQ scheme. The Rs. 48.9 lakh funding supports her groundbreaking project on antimicrobial therapeutics, underscoring the importance and potential impact of her work. Chemical Biology This recognition highlights her role as a leading researcher in her field.

IMPACT AND INFLUENCE 🌍

Jhuma Bhadra’s research impacts both the scientific community and broader society. Her work on nucleolipids and antimicrobial therapeutics addresses pressing health issues, contributing to the development of new strategies to combat bacterial infections. By integrating her research findings into her teaching, she influences and inspires her students, fostering a new wave of Chemical Biology scientific inquiry and innovation in chemistry.

LEGACY AND FUTURE CONTRIBUTIONS 💡

Jhuma’s legacy in the field of chemistry is characterized by her innovative approach to research and her commitment to education. As she continues her work at Sarojini Naidu College for Women, her contributions are poised to expand the frontiers of nucleolipid research and antimicrobial therapies. Her future endeavors will likely include further exploration of biomedical applications, continuing to bridge the gap between fundamental research and practical healthcare solutions. Jhuma Bhadra’s dedication ensures her lasting influence in the realm of chemical sciences and beyond.

NOTABLE PUBLICATIONS

Title: Peptide Nucleic Acids: Recent Advancements and Future Opportunities in Biomedical Applications
Authors: Achinta Sannigrahi, Nayan De, Debmalya Bhunia, Jhuma Bhadra
Journal: Bioorganic Chemistry
DOI: 10.1016/j.bioorg.2025.108146
Title: Understanding Antisense Oligonucleotide Efficiency in Inhibiting Prokaryotic Gene Expression
Authors: Sandra Story, Sayantan Bhaduri, Sudakshina Ganguly, Rambabu Dakarapu, Sarah L. Wicks, Jhuma Bhadra, Simeon Kwange, Dev Arya
Journal: ACS Infectious Diseases
DOI: 10.1021/acsinfecdis.3c00645
Title: Self-Transfecting GMO-PMO Chimera Targeting Nanog Enable Gene Silencing In Vitro and Suppresses Tumor Growth in 4T1 Allografts in Mouse
Authors: Ujjal Das, Jayanta Kundu, Pallab Shaw, Chandra Bose, Atanu Ghosh, Shalini Gupta, Sudipta Sarkar, Jhuma Bhadra, Surajit Sinha
Journal: Molecular Therapy - Nucleic Acids
DOI: 10.1016/j.omtn.2023.03.011
Title: Cananginone Abrogates EMT in Breast Cancer Cells through Hedgehog Signaling
Authors: Chandra Bose, Ujjal Das, Tapan Kumar Kuilya, Joyanta Mondal, Jhuma Bhadra, Priyanjalee Banerjee, Rajib Kumar Goswami, Surajit Sinha
Journal: Chemistry & Biodiversity
DOI: 10.1002/cbdv.202100823
Title: Self-Transfecting GMO-PMO and PMO-GMO Chimeras Enable Gene Silencing In Vitro and In Vivo Zebrafish Model and NANOG Inhibition Induce the Apoptosis in Breast and Prostate Cancer Cells
Authors: Jayanta Kundu, Ujjal Das, Chandra Bose, Jhuma Bhadra, Surajit Sinha
Journal: Preprint
DOI: 10.1101/2021.06.04.447039

🎓 EARLY ACADEMIC PURSUITS

Mabrouk Attia Abd Eldaim embarked on his academic journey with a Bachelor of Veterinary Medical Sciences from Alexandria University, Egypt, in May 1997, graduating with a rank of "Very Good." His passion for veterinary medicine and biochemistry led him to pursue a Master of Veterinary Medical Sciences with a focus on physiology at Menoufia University, which he completed in June 2003. Driven by a deep curiosity in molecular biology, he continued his education in Japan, obtaining a Ph.D. in Biochemistry and Molecular Biology from Hokkaido University in September 2010. His dedication to advancing his expertise was further demonstrated through two post-doctoral fellowships in Biomedical Sciences at Kyoto University, Japan, in October 2013 and February 2018.

💼 PROFESSIONAL ENDEAVORS

Dr. Abd Eldaim holds the esteemed position of Vice Dean for Postgraduate Affairs at the Faculty of Veterinary Medicine, Menoufia University, Egypt. He also serves as a Professor of Biochemistry and Molecular Biology in the same department. His role as the Director of the Quality Assurance and Accreditation Unit at the Faculty underscores his commitment to maintaining high academic standards and promoting excellence in education. Prior to his current roles, he has held various positions including Associate Professor at both Menoufia University and the University of Sadat City, as well as Lecturer and Assistant Lecturer in physiology and biochemistry.

🔬 CONTRIBUTIONS AND RESEARCH FOCUS

Dr. Abd Eldaim's research is centered on biochemistry and molecular biology, with a particular emphasis on understanding biochemical processes and their implications in veterinary science. His work spans a range of topics including metabolic pathways, molecular mechanisms of diseases, and the development of diagnostic and therapeutic approaches. His research contributions are reflected in his extensive publication Biochemistry and Molecular Biology record and his active participation in advancing the field through both teaching and research.

🏆 ACCOLADES AND RECOGNITION

Throughout his career, Dr. Abd Eldaim has achieved significant recognition for his scientific contributions. His research has garnered a notable citation index, with a total of 686 citations on Scopus and 1121 on Google Scholar, indicating the impactful nature of his work. He is also Biochemistry and Molecular Biology recognized for his scholarly excellence and his role in advancing veterinary biochemistry and molecular biology through his academic positions and research contributions.

🌍 IMPACT AND INFLUENCE

Dr. Abd Eldaim's influence extends beyond his immediate academic environment. His research has contributed to a deeper understanding of biochemical processes and their relevance to veterinary science. His role as an educator has shaped the careers of numerous students, Biochemistry and Molecular Biology equipping them with the knowledge and skills necessary for advancing the field. His leadership in quality assurance and accreditation also plays a crucial role in maintaining the high standards of education and research at Menoufia University.

🏛️ LEGACY AND FUTURE CONTRIBUTIONS

Dr. Abd Eldaim's legacy is characterized by his dedication to advancing veterinary biochemistry and molecular biology through both research and education. His ongoing efforts to improve the quality of postgraduate education and his contributions to scientific knowledge ensure that his impact will continue to be felt in the field. As he moves forward, Dr. Abd Eldaim remains committed to exploring new frontiers in biochemistry and molecular biology, fostering the next generation of scientists, and contributing to the advancement of veterinary medicine.