Ivana Vieira De Mello Loureiro | Mucosal Associated Lymphoid Tissue | Visionary Research Impact Award 

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Dr. Ivana Vieira De Mello Loureiro | Mucosal Associated Lymphoid Tissue | Visionary Research Impact Award 

BUTANTAN INSTITUTE  |  Brazil

Dr. Ivana Vieira De Mello Loureiro cultivated a distinguished path in immunology from her medical graduation to advanced research, with a doctorate focused on human colostrum IgA antibodies reactive with colonization and pathogenic factors of Escherichia coli enteropathogenic strains. she subsequently served at the renowned Instituto Butantan as a full-time scientific technical research assistant, contributing to flow cytometry, immunopathology and training of students in immunological methods. her work spans immunology, immune response regulation and microbiology, bringing together applied immunology and human health sectors via investigations of peyer’s patches, oral BCG immunization, lymphocyte responses and hormonal influence on B cells emerging from the gut-associated lymphoid tissue. although precise citation-metrics (h-index, total documents, citations) are not publicly available from the source consulted, she is a seasoned researcher whose legacy lies in immunological characterisation of human colostral IgA, functional assays and flow-cytometric applications in immunopathology. her influence is evident in the training of scientists, implementation of cytometry services, and bridging of basic immunological research with maternal-infant health contexts. her legacy continues as she remains active in specialised technician-scientific roles, supporting immunology research infrastructure and mentoring future generations, thereby ensuring her contributions will endure well into emerging immunological challenges.

Profile: Orcid 

Featured Publications 

Loureiro Vieira de Mello, I. V., & Alves de Araujo, C. A. (2025). Impact of oral Bacillus Calmette–Guérin on B220 receptor expression in Peyer’s patches of lactating mice: Analysis of receptor percentiles and cell frequencies. Journal of Immunological Methods.

Loureiro, I., Frankel, G., Adu-Bobie, J., Dougan, G., Trabulsi, L. R., & Carneiro-Sampaio, M. M. S. (1998, August). Human colostrum contains IgA antibodies reactive to enteropathogenic Escherichia coli virulence-associated proteins: Intimin, BfpA, EspA, and EspB. Journal of Pediatric Gastroenterology & Nutrition, 27(2), 166–171.

Loureiro, I., & Mota, I. (1993, July 1). Decrease in passive cutaneous anaphylaxis reactions in rats secondary to stress. Brazilian Journal of Medical and Biological Research, 26(7), 749–752.

Loureiro, I., & Wada, C. Y. (1993, January). Influence of stress on IgE production. Physiology & Behavior, 53(1), 45–49.

Dr. Frédérique Vegran – immuno oncology –  Best Researcher Award

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Dr. Frédérique Vegran - immuno oncology -  Best Researcher Award

INSERM - France

Author Profile 

GOOGLE SCHOLAR 

🎓 Early academic pursuits

Frédérique Vegran began her scientific journey with a strong foundation in cellular and molecular biology, earning her phd in this domain. during her early academic years, she exhibited a keen interest in understanding cellular behavior under varying physiological conditions. this led her to pursue advanced studies and training in belgium, where she spent three years as a post-doctoral researcher. her research during this time revolved around the tumor microenvironment, hypoxia, and metabolic regulation—areas that laid the groundwork for her future focus in immuno-oncology, a field now evolving alongside advancements in power electronics and biotechnology integration.

🧪 Professional endeavors

Currently a full-time research scientist at inserm umr1231 in dijon, france, frédérique vegran has established herself as a leading figure in immuno-oncology. her professional tenure is marked by active involvement in cutting-edge research aimed at enhancing anti-tumor immune responses. she has supervised multiple phd candidates and participated in thesis evaluation committees, highlighting her commitment to nurturing future generations of scientists. her involvement in research also bridges academic curiosity with translational potential—something akin to the precision and adaptability found in modern power electronics systems.

🔬 Contributions and research focus

Vegran’s groundbreaking contributions have significantly advanced our understanding of t cell biology in cancer. one of her landmark findings includes the role of il-1b in promoting the anti-tumor effect of th9 cells (nature immunology, 2013). she also revealed a novel transcriptional function of nlrp3 in th2 cells (nature immunology, 2015), and more recently, identified the immuno oncology regulatory role of nlrp3 in th17 differentiation and its acquisition of treg-like properties within tumor environments (cellular and molecular immunology, 2025). such insights have reinforced the importance of targeted immune modulation—an idea resonating with the fine-tuning concepts used in power electronics.

🌍 Impact and influence

Her influence extends beyond publications, with an h-index of 37 and i10 index of 52, demonstrating consistent citation and global recognition of her work. having authored over 67 peer- immuno oncology reviewed articles, including in top-tier journals, frédérique vegran continues to impact the scientific discourse in immuno-oncology. her discoveries have paved new avenues for therapeutic strategies, inspiring researchers globally to explore the interplay between immune cells and cancer. her professional memberships with the french society of immunology (sfi) and the french society for immunotherapy of cancer (fitc) further signify her standing in the field.

📊 Academic cites

Vegran’s academic output is notable with 67 journal publications indexed in scopus and sci, alongside 8 completed and 3 ongoing research projects. she has contributed to 3 immuno oncology consultancy/industry-related projects and has 2 patents published, highlighting her dual focus on innovation and application. although she has not authored books, her work stands as a valuable reference across the immunological and oncological academic landscapes.

🧬 Legacy and future contributions

Frédérique Vegran’s legacy lies in the transformative nature of her research on immune modulation in cancer. her consistent engagement in phd mentorship, cutting-edge experimentation, and scientific evaluation sets a strong example for academic leadership. looking ahead, her research is poised to further decode immune-cancer interactions, potentially contributing to the development of novel therapeutic interventions that integrate cellular biology with advanced technologies, much like how power electronics revolutionized modern engineering systems.

Notable Publications 

  1. Title: Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
    Authors: P. Sonveaux, F. Végran, T. Schroeder, M.C. Wergin, J. Verrax, Z.N. Rabbani, ...
    Journal: The Journal of Clinical Investigation

  2. Title: Lactate influx through the endothelial cell monocarboxylate transporter MCT1 supports an NF-κB/IL-8 pathway that drives tumor angiogenesis
    Authors: F. Végran, R. Boidot, C. Michiels, P. Sonveaux, O. Feron
    Journal: Cancer Research

  3. Title: Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth
    Authors: M. Bruchard, G. Mignot, V. Derangère, F. Chalmin, A. Chevriaux, F. Végran, ...
    Journal: Nature Medicine

  4. Title: Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis
    Authors: P. Sonveaux, T. Copetti, C.J. De Saedeleer, F. Vegran, J. Verrax, ...
    Journal: PLOS ONE

  5. Title: The receptor NLRP3 is a transcriptional regulator of TH2 differentiation
    Authors: M. Bruchard, C. Rebé, V. Derangère, D. Togbé, B. Ryffel, R. Boidot, ...
    Journal: Nature Immunolog

Prof. Mingqian fang – Immunology & Hematology – Women Researcher Award

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Prof. Mingqian fang - Immunology & Hematology - Women Researcher Award

Kunming Institute of Zoology, Chinese Academy of Sciences - Zimbabwe

Author Profile

ORCID 

Early academic pursuits 🎓

Mingqian fang embarked on his academic journey with a keen interest in biology and medical sciences, eventually specializing in the study of disease pathogenesis. his early work centered on understanding how infections and inflammatory responses influence mental health, particularly focusing on stress-induced depression. his educational background laid a strong foundation for his future research in both neuroscience and cardiovascular diseases. as a professor at the kunming institute of zoology, chinese academy of sciences, he has consistently contributed to groundbreaking research.

Professional endeavors 🏢

As a professor at the kunming institute of zoology, mingqian has dedicated his career to exploring the connections between stress, depression, and physiological responses to infections. his research has not only deepened our understanding of how stress exacerbates mental health disorders, but has also opened pathways to developing effective treatments for both depression and cardiovascular diseases. his expertise extends to studying natural toxin peptides, with particular focus on their biomedical applications.

Contributions and research focus 🔬

Mingqian’s primary research areas include the pathogenesis of diseases like depression under stressful stimuli, such as infections and inflammation, and the Immunology & Hematology development of innovative drugs to treat these conditions. his notable work includes the discovery of how lipopolysaccharide-binding protein expression is increased by stress, promoting depressive symptoms by inhibiting monoamine synthesis. he has also explored the role of bat-derived peptides and how they impact neuroinflammation, contributing significantly to the understanding of the body's immune response to various stressors.

Accolades and recognition 🏅

Mingqian fang’s research has been widely recognized in the scientific community, with publications in high-impact journals such as immunity and pnas. his works have earned accolades due to their novel insights into how biological systems respond to stress and disease. his research in immune responses and toxin peptides has Immunology & Hematology been acknowledged globally, with his papers being published in top-tier journals with high impact factors, demonstrating the importance and quality of his findings.

Impact and influence 🌍

Mingqian’s research has had a far-reaching impact on both neuroscience and cardiovascular medicine. by linking mental health issues like depression to biological processes such as inflammation, he has paved the way for new treatment methodologies. his work on natural toxins also holds promise for creating innovative drugs Immunology & Hematology that could target specific disease mechanisms, further influencing the pharmaceutical industry and biomedical research. his influence spans across multiple fields, combining neuroscience, immunology, and pharmacology.

Legacy and future contributions 🔮

Mingqian fang’s ongoing work ensures that his legacy in the scientific world continues to grow. his pioneering research on stress-related depression and cardiovascular conditions is laying the groundwork for future innovations in drug development. by bridging the gap between neuroscience and immunology, his research will likely inspire further interdisciplinary studies aimed at improving human health. his work on bat-derived peptides, in particular, opens exciting possibilities for novel therapies.

Notable Publications 

  • Title: The Price of P2X7R Freedom is Neuroinflammation
    Authors: Fang M, Lai R
    Journal: Immunity
    Date: March 2024
    DOI: 10.1016/j.immuni.2024.02.009
  • Title: Transferrin Is Up-Regulated by Microbes and Acts as a Negative Regulator of Immunity to Induce Intestinal Immunotolerance
    Authors: Tang X, Fang M, Cheng R, Niu J, Huang X, Xu K, Wang G, Sun Y, Liao Z, Zhang Z et al.
    Journal: Research (Washington, D.C.)
    Date: January 2024
    DOI: 10.34133/research.0301
  • Title: Lipopolysaccharide-Binding Protein Expression is Increased by Stress and Inhibits Monoamine Synthesis to Promote Depressive Symptoms
    Authors: Fang M, Li Y, Liao Z, Wang G, Cao Q, Li Y, Duan Y, Han Y, Deng X, Wu F et al.
    Journal: Immunity
    Date: February 2023
    DOI: 10.1016/j.immuni.2023.02.002
  • Title: An Undefined Cystatin CsCPI1 from Tea Plant Camellia sinensis Harbors Antithrombotic Activity
    Authors: Fang M, Cha JH, Wang HC, Ye P, Chen B, Chen M, Yang WH, Yan X
    Journal: Biomedicine & Pharmacotherapy
    Date: January 2023
    DOI: 10.1016/j.biopha.2023.114285
  • Title: Hypoxia and Low Temperature Upregulate Transferrin to Induce Hypercoagulability at High Altitude
    Authors: Li M, Tang X, Liao Z, Shen C, Cheng R, Fang M, Wang G, Li Y, Tang S, Xie L et al.
    Journal: Blood
    Date: November 2022
    DOI: 10.1182/blood.2022016410