Shiraz University| Iran

Mohammad Sadegh Taghizadeh is based at the Agricultural Faculty of Shiraz University (Institute of Biotechnology, Shiraz-Isfahan Highway, Shiraz, Iran) where he pursues advanced research in bioactive small molecules and peptides—whether synthesised by ribosomes or derived from proteins. His work spans in vitro isolation, purification and structural-physicochemical characterisation of these compounds, their pharmacological and sensory properties, and complementary in silico design and target-interaction studies. He also explores recombinant production of bioactive peptides using plant and bacterial expression systems. Prior to his current role, he earned a bachelor’s in agricultural engineering (plant protection) at Shahid Bahonar University of Kerman, a master’s in plant biotechnology at University of Guilan (thesis: factors affecting virulence genes of Agrobacterium tumefaciens in Arabidopsis thaliana mutants), and a PhD in biotechnology at Shiraz University (dissertation: functional properties of bio-active peptides derived from plant resources). He gained research experience at the Medical University of Vienna (on discovery of a novel cyclotide targeting the CCK2 receptor) and later led a project on plant-derived bioinsecticides funded by the National Elite Foundation of Iran, while also teaching as a TA in plant genetic engineering, molecular markers and plant tissue culture at Shiraz University. His research has steadily contributed to the field of peptide biotechnology, with growing recognition: his h-index currently stands at (unknown) and his publication and citation counts are steadily rising as he continues to establish himself in the realm of bioactive small molecules and recombinant peptide production.

Featured Publications

Abbasi, A., Taghizadeh, M. S., Moghadam, A., Niazi, A., Lotfi, M., & Taghavi, S.-M. (2025). A comprehensive insight into ultrasound-assisted protein extraction from Camelina sativa and de-bittering of resulting hydrolysates with emphasis on their structural, physicochemical, sensory, and biological properties. Food Chemistry, 445, 145435.

Taghizadeh, M. S., Niazi, A., Mirzapour-Kouhdasht, A., Pereira, E. C., & Garcia-Vaquero, M. (2025). Enhancing cyclotide bioproduction: Harnessing biological synthesis methods and various expression systems for large-scale manufacturing. Critical Reviews in Biotechnology, 45(1), 1–20.

Hoseini, S., Moghadam, A., Palizban, A., Hoseini, F., Taghizadeh, M. S., Choopani, A., & Hoseini, F. (2025). Immune boosting by pharmaceutical C-phycocyanin, in vitro and in silico effects on peripheral blood mononuclear cells. Health Biotechnology and Biopharma, 8(1), 1–10.

Lotfi, M., Keshvari, T., Taghizadeh, M. S., Afsharifar, A., Moghadam, A., Aram, F., & Niazi, A. (2025). Optimizing Camelina sativa oil extraction and its cytotoxicity using RSM by emphasis on antioxidant properties, physical characteristics, and molecular docking insights. Industrial Crops and Products, 215, 120334.

Taghizadeh, M. S., Mirzapour-Kouhdasht, A., & Huang, J.-Y. (2025, December). Unraveling the structure-activity relationship and molecular mechanisms for targeted therapeutic applications of food-derived angiotensin-I-converting enzyme inhibitory peptides. Food Bioscience, 65, 107820.

Prof. Mrinal k ghosh - Cancer Therapy - Outstanding Scientist Award

CSIR-Indian Institute of Chemical Biology - India

Author Profile

SCOPUS

🎓 Early academic pursuits

Dr. Mrinal k ghosh earned his b.sc., m.sc., and phd in biochemistry from the university of calcutta, india. his academic journey was characterized by a strong foundation in molecular biology and biochemistry, leading to a prolific research career in cancer biology and inflammatory disorders.

🏢 Professional endeavors

Dr. Ghosh has held various prestigious positions at csir-indian institute of chemical biology, culminating in his current role as chief scientist. his international experience includes post-doctoral research at the cleveland clinic foundation, usa, and academic roles in india, contributing significantly to cancer research and molecular biology.

🔄 Contributions and research focus

Specializing in cancer biology and inflammatory disorders, dr. ghosh has developed groundbreaking research in signal transduction in cancer and stem cells. his work has led to numerous Cancer Therapy publications, patents, and collaborative projects that have advanced the understanding and treatment of cancer.

🏆 Accolades and recognition

His numerous accolades include the bharat vikash award, fellowships from the national academy of science and technology, and the outstanding scientist award. his role as a reviewer for top Cancer Therapy journals and evaluator for national and international projects further highlights his academic stature.

👨‍👩‍👦 Impact and influence

Dr. Ghosh's influence extends beyond his research, impacting policy-making, academic standards, and translational research in india. his leadership roles within csir-iicb and various academic Cancer Therapy committees have shaped the future of scientific research in the country.

🌟 Legacy and future contributions

Dr. Ghosh's legacy is defined by his contributions to cancer biology, his mentorship of future scientists, and his commitment to advancing biomedical research. his ongoing work promises continued innovation and significant contributions to cancer therapy and molecular biology.

Notable Publications

Title: The key vulnerabilities and therapeutic opportunities in the USP7-p53/MDM2 axis in cancer
Author(s): Gouranga Saha, Mrinal Kanti Ghosh
Journal: BBA - Molecular Cell Research, 2025
Title: Phenolato and alkoxo promoted change in the ligand coordination mode in a four-membered ortho-metalated ruthenium(II) organometallics
Author(s): Mrinal Kanti Ghosh, Jagannath Chowdhury, Purnananda Garu, Indranil Chakraborty, Swarup Chattopadhyay
Journal: Polyhedron, 2025
Title: Carbon Nanotubes in Cancer Diagnosis and Treatment: Current Trends and Future Perspectives
Author(s): Sunny Kumar, Aafreen Ansari, Malini Basu, Sabana Begam, Mrinal Kanti Ghosh
Journal: Advanced Therapeutics, 2025
Title: E3 ubiquitin ligases and deubiquitinases in colorectal cancer: Emerging molecular insights and therapeutic opportunities
Author(s): Sunny Kumar, Malini Basu, Mrinal Kanti Ghosh
Journal: BBA - Molecular Cell Research, 2024
Title: Chromosomal instability (CIN) triggers immune evasion and metastatic potential in cancer through rewired STING signalling
Author(s): Mrinal Kanti Ghosh, Srija Roy
Journal: Molecular Biomedicine, 2024

Mohammad Sadegh Taghizadeh | Drug Discovery | Best Researcher Award

Dr. Mohammad Sadegh Taghizadeh | Drug Discovery | Best Researcher Award

Shiraz University| Iran

Featured Publications