Assoc. Prof. Dr. Jun Xiu sheng - Cancer treatment - Best Researcher Award

The First Affiliated Hospital of Dalian Medical University - China

Author Profile

🎓 Early academic pursuits

Jun Xiu sheng began his academic journey with a strong foundation in clinical medicine. from 2006 to 2011, he pursued a seven-year undergraduate program in clinical medicine at dalian medical university, followed by graduate studies from 2011 to 2013 at the same institution. in 2013, he embarked on a ph.d. in oncology at the graduate school of dalian medical university, sharpening his focus on cancer biology and therapy. his academic path was further enriched through a prestigious exchange scholar program at the medical university of wisconsin, usa, from 2015 to 2016, where he gained international exposure and research insight.

🩺 Professional endeavors

After completing his advanced education, jun xiu sheng joined the first affiliated hospital of dalian medical university. he served as a resident in the department of radiotherapy from 2016 to 2018 and quickly rose through the ranks to become an attending physician (2018–2020). since december 2020, he has held the position of deputy chief physician, where he also serves as an associate professor. his clinical expertise lies in radiation oncology, contributing to the development of novel therapeutic strategies in cancer care. jun xiu sheng’s interest in interdisciplinary approaches, including those inspired by power electronics systems, has made his clinical methods highly adaptive and innovative.

🔬 Contributions and research focus

With a ph.d. in oncology, jun xiu sheng has dedicated his research efforts to understanding the molecular and cellular mechanisms behind tumor resistance and radiotherapy. his recent work explores how melatonin modulates rna splicing in esophageal cancer cells, potentially increasing radiotherapy sensitivity. melatonin, known for its use in treating central nervous system Cancer treatment diseases, has shown promise in suppressing tumor growth. through bioinformatics and rna-seq analysis, jun xiu sheng has investigated the role of variable splicing in radiation resistance, aiming to unlock therapeutic pathways to improve cancer treatment outcomes. integrating ideas from power electronics systems, he also explores regulatory networks in tumor biology.

🌍 Impact and influence

Jun Xiu sheng’s research has not only advanced our understanding of cancer biology but also influenced therapeutic strategies in radiation oncology. by uncovering mechanisms related to rna Cancer treatment variable splicing and the effects of melatonin on tumor cells, he has provided critical insight into resistance pathways. his collaborative roles in national-level projects, including the national natural science foundation of china, have elevated his profile within the academic and medical communities. his interdisciplinary thinking, including applying models from power electronics, offers new paradigms in cancer signal processing and therapy modulation.

📚 Academic cites

Jun Xiu sheng has participated in several major research projects. he contributed to a study on circular rna generation funded by the national natural science foundation of china, and another Cancer treatment on the function of rna variable splicing in tumor radiotherapy resistance. as a principal investigator, he led projects on aspirin-induced rna splicing in lung cancer and on the immune regulation of head and neck squamous cell carcinoma (hnscc). his ongoing research into esophageal cancer immunotherapy and prognosis demonstrates a sustained commitment to scholarly contribution and scientific innovation.

🧬 Legacy and future contributions

Looking forward, jun xiu sheng is committed to deepening his exploration of tumor microenvironments, radiotherapy resistance mechanisms, and immune system interactions in cancer. his current projects funded by liaoning provincial programs and education departments reflect his active role in shaping the future of oncology. he envisions integrating computational and systemic models—akin to feedback loops found in power electronics—to decode complex biological responses in tumors. his legacy will be defined by a blend of rigorous scientific inquiry, clinical excellence, and forward-thinking applications in precision medicine.

Notable Publications

Title: The role of oncostatin M in esophageal cancer and its potential as a prognostic marker
Author(s): Guangxiang Ding, Xianwei Li, Hongtao Yin, Bing Sun, Junxiu Sheng
Journal: Computers in Biology and Medicine, 2025

🎓 Early academic pursuits

Chanchal Choudhary’s academic journey began with a deep interest in molecular and developmental biology. She pursued a Doctor of Philosophy (PhD) in Life Sciences at Jawaharlal Nehru University, New Delhi. Her coursework, completed with an impressive CGPA of 8.06, laid a strong foundation in the intricacies of developmental biology. Her PhD research, titled "Understanding the role of TCTP2 in Dictyostelium discoideum," delved into the molecular dynamics of Translationally Controlled Tumor Protein (TCTP) and its critical role in various cellular processes.

🏢 Professional endeavors

Chanchal has amassed extensive experience in independent research and has been at the forefront of high-impact studies. Her work has led to several peer-reviewed publications and presentations at international conferences. This trajectory has not only honed her expertise but also positioned her as a leader in cross-functional projects. She has demonstrated a strong capability to mentor emerging scientists, fostering an environment of growth and innovation within her research teams.

🔬 Contributions and research focus

The cornerstone of Chanchal’s research lies in her in-depth exploration of TCTP2 in Dictyostelium discoideum. Her findings reveal the protein’s pivotal role in autophagy regulation, which is Molecular and Developmental Biology crucial for understanding cell proliferation, survival, and death. By elucidating the functions of TPT2, her research offers valuable insights into cellular dynamics and developmental biology. This study not only advances basic biological knowledge but also underscores the therapeutic potential of targeting TCTP in cancer treatment.

🌟 Accolades and recognition

Chanchal’s scholarly contributions have earned her recognition in the scientific community. Her research findings, published in esteemed journals, reflect her dedication and innovative Molecular and Developmental Biology approach. She has presented her work at prestigious international conferences, where she has been commended for her clarity and depth of knowledge. These accolades highlight her commitment to advancing the field of molecular and developmental biology.

🌍 Impact and influence

Chanchal’s work has significantly impacted the understanding of cellular processes in both basic and applied sciences. Her research on TCTP2 in Dictyostelium discoideum provides a Molecular and Developmental Biology framework for further studies on cell proliferation and autophagy. This has far-reaching implications for cancer research, potentially paving the way for novel therapeutic strategies. Her mentorship and collaborative projects have also influenced the next generation of scientists, fostering a culture of inquiry and discovery.

📚 Legacy and future contributions

Chanchal Choudhary’s legacy is rooted in her groundbreaking research and her dedication to the scientific community. As she continues her career, her future contributions are anticipated to further unravel the complexities of molecular biology and its applications in health and disease. Her ongoing commitment to addressing biological challenges through innovative research promises to leave a lasting impact on the field.

Notable Publications

Title: Analyzing the functions of Translationally controlled tumor protein2 during growth, development and autophagy of Dictyostelium discoideum
Authors: Chanchal Choudhary, Bhavya Jain, Shweta Saran
Journal: Experimental Cell Research
DOI: 10.1016/j.yexcr.2024.114400
ISSN: 0014-4827
Publication Date: January 2025

Title: In silico analysis of Translationally-Controlled Tumour Proteins of social amoeba Dictyostelium discoideum
Authors: Chanchal Choudhary, Shweta Saran
Journal: Biospectra
DOI: 10.5281/ZENODO.14062730
Publication Date: January 15, 2024