Mohammad Sadegh Taghizadeh | Drug Discovery | Best Researcher Award

Dr. Mohammad Sadegh Taghizadeh | Drug Discovery | Best Researcher Award

Shiraz University| Iran

Mohammad Sadegh Taghizadeh is based at the Agricultural Faculty of Shiraz University (Institute of Biotechnology, Shiraz-Isfahan Highway, Shiraz, Iran) where he pursues advanced research in bioactive small molecules and peptides—whether synthesised by ribosomes or derived from proteins. His work spans in vitro isolation, purification and structural-physicochemical characterisation of these compounds, their pharmacological and sensory properties, and complementary in silico design and target-interaction studies. He also explores recombinant production of bioactive peptides using plant and bacterial expression systems. Prior to his current role, he earned a bachelor’s in agricultural engineering (plant protection) at Shahid Bahonar University of Kerman, a master’s in plant biotechnology at University of Guilan (thesis: factors affecting virulence genes of Agrobacterium tumefaciens in Arabidopsis thaliana mutants), and a PhD in biotechnology at Shiraz University (dissertation: functional properties of bio-active peptides derived from plant resources). He gained research experience at the Medical University of Vienna (on discovery of a novel cyclotide targeting the CCK2 receptor) and later led a project on plant-derived bioinsecticides funded by the National Elite Foundation of Iran, while also teaching as a TA in plant genetic engineering, molecular markers and plant tissue culture at Shiraz University. His research has steadily contributed to the field of peptide biotechnology, with growing recognition: his h-index currently stands at (unknown) and his publication and citation counts are steadily rising as he continues to establish himself in the realm of bioactive small molecules and recombinant peptide production.

Profile: Orcid  |  Scopus 

Featured Publications 

Abbasi, A., Taghizadeh, M. S., Moghadam, A., Niazi, A., Lotfi, M., & Taghavi, S.-M. (2025). A comprehensive insight into ultrasound-assisted protein extraction from Camelina sativa and de-bittering of resulting hydrolysates with emphasis on their structural, physicochemical, sensory, and biological properties. Food Chemistry, 445, 145435.

Taghizadeh, M. S., Niazi, A., Mirzapour-Kouhdasht, A., Pereira, E. C., & Garcia-Vaquero, M. (2025). Enhancing cyclotide bioproduction: Harnessing biological synthesis methods and various expression systems for large-scale manufacturing. Critical Reviews in Biotechnology, 45(1), 1–20.

Hoseini, S., Moghadam, A., Palizban, A., Hoseini, F., Taghizadeh, M. S., Choopani, A., & Hoseini, F. (2025). Immune boosting by pharmaceutical C-phycocyanin, in vitro and in silico effects on peripheral blood mononuclear cells. Health Biotechnology and Biopharma, 8(1), 1–10.

Lotfi, M., Keshvari, T., Taghizadeh, M. S., Afsharifar, A., Moghadam, A., Aram, F., & Niazi, A. (2025). Optimizing Camelina sativa oil extraction and its cytotoxicity using RSM by emphasis on antioxidant properties, physical characteristics, and molecular docking insights. Industrial Crops and Products, 215, 120334.

Taghizadeh, M. S., Mirzapour-Kouhdasht, A., & Huang, J.-Y. (2025, December). Unraveling the structure-activity relationship and molecular mechanisms for targeted therapeutic applications of food-derived angiotensin-I-converting enzyme inhibitory peptides. Food Bioscience, 65, 107820.