Ivana Vieira De Mello Loureiro | Mucosal Associated Lymphoid Tissue | Visionary Research Impact Award 

Dr. Ivana Vieira De Mello Loureiro | Mucosal Associated Lymphoid Tissue | Visionary Research Impact Award 

BUTANTAN INSTITUTE  |  Brazil

Dr. Ivana Vieira De Mello Loureiro cultivated a distinguished path in immunology from her medical graduation to advanced research, with a doctorate focused on human colostrum IgA antibodies reactive with colonization and pathogenic factors of Escherichia coli enteropathogenic strains. she subsequently served at the renowned Instituto Butantan as a full-time scientific technical research assistant, contributing to flow cytometry, immunopathology and training of students in immunological methods. her work spans immunology, immune response regulation and microbiology, bringing together applied immunology and human health sectors via investigations of peyer’s patches, oral BCG immunization, lymphocyte responses and hormonal influence on B cells emerging from the gut-associated lymphoid tissue. although precise citation-metrics (h-index, total documents, citations) are not publicly available from the source consulted, she is a seasoned researcher whose legacy lies in immunological characterisation of human colostral IgA, functional assays and flow-cytometric applications in immunopathology. her influence is evident in the training of scientists, implementation of cytometry services, and bridging of basic immunological research with maternal-infant health contexts. her legacy continues as she remains active in specialised technician-scientific roles, supporting immunology research infrastructure and mentoring future generations, thereby ensuring her contributions will endure well into emerging immunological challenges.

Profile: Orcid 

Featured Publications 

Loureiro Vieira de Mello, I. V., & Alves de Araujo, C. A. (2025). Impact of oral Bacillus Calmette–Guérin on B220 receptor expression in Peyer’s patches of lactating mice: Analysis of receptor percentiles and cell frequencies. Journal of Immunological Methods.

Loureiro, I., Frankel, G., Adu-Bobie, J., Dougan, G., Trabulsi, L. R., & Carneiro-Sampaio, M. M. S. (1998, August). Human colostrum contains IgA antibodies reactive to enteropathogenic Escherichia coli virulence-associated proteins: Intimin, BfpA, EspA, and EspB. Journal of Pediatric Gastroenterology & Nutrition, 27(2), 166–171.

Loureiro, I., & Mota, I. (1993, July 1). Decrease in passive cutaneous anaphylaxis reactions in rats secondary to stress. Brazilian Journal of Medical and Biological Research, 26(7), 749–752.

Loureiro, I., & Wada, C. Y. (1993, January). Influence of stress on IgE production. Physiology & Behavior, 53(1), 45–49.

Prof. Mingqian fang – Immunology & Hematology – Women Researcher Award

Prof. Mingqian fang - Immunology & Hematology - Women Researcher Award

Kunming Institute of Zoology, Chinese Academy of Sciences - Zimbabwe

Author Profile

ORCID 

Early academic pursuits 🎓

Mingqian fang embarked on his academic journey with a keen interest in biology and medical sciences, eventually specializing in the study of disease pathogenesis. his early work centered on understanding how infections and inflammatory responses influence mental health, particularly focusing on stress-induced depression. his educational background laid a strong foundation for his future research in both neuroscience and cardiovascular diseases. as a professor at the kunming institute of zoology, chinese academy of sciences, he has consistently contributed to groundbreaking research.

Professional endeavors 🏢

As a professor at the kunming institute of zoology, mingqian has dedicated his career to exploring the connections between stress, depression, and physiological responses to infections. his research has not only deepened our understanding of how stress exacerbates mental health disorders, but has also opened pathways to developing effective treatments for both depression and cardiovascular diseases. his expertise extends to studying natural toxin peptides, with particular focus on their biomedical applications.

Contributions and research focus 🔬

Mingqian’s primary research areas include the pathogenesis of diseases like depression under stressful stimuli, such as infections and inflammation, and the Immunology & Hematology development of innovative drugs to treat these conditions. his notable work includes the discovery of how lipopolysaccharide-binding protein expression is increased by stress, promoting depressive symptoms by inhibiting monoamine synthesis. he has also explored the role of bat-derived peptides and how they impact neuroinflammation, contributing significantly to the understanding of the body's immune response to various stressors.

Accolades and recognition 🏅

Mingqian fang’s research has been widely recognized in the scientific community, with publications in high-impact journals such as immunity and pnas. his works have earned accolades due to their novel insights into how biological systems respond to stress and disease. his research in immune responses and toxin peptides has Immunology & Hematology been acknowledged globally, with his papers being published in top-tier journals with high impact factors, demonstrating the importance and quality of his findings.

Impact and influence 🌍

Mingqian’s research has had a far-reaching impact on both neuroscience and cardiovascular medicine. by linking mental health issues like depression to biological processes such as inflammation, he has paved the way for new treatment methodologies. his work on natural toxins also holds promise for creating innovative drugs Immunology & Hematology that could target specific disease mechanisms, further influencing the pharmaceutical industry and biomedical research. his influence spans across multiple fields, combining neuroscience, immunology, and pharmacology.

Legacy and future contributions 🔮

Mingqian fang’s ongoing work ensures that his legacy in the scientific world continues to grow. his pioneering research on stress-related depression and cardiovascular conditions is laying the groundwork for future innovations in drug development. by bridging the gap between neuroscience and immunology, his research will likely inspire further interdisciplinary studies aimed at improving human health. his work on bat-derived peptides, in particular, opens exciting possibilities for novel therapies.

Notable Publications 

  • Title: The Price of P2X7R Freedom is Neuroinflammation
    Authors: Fang M, Lai R
    Journal: Immunity
    Date: March 2024
    DOI: 10.1016/j.immuni.2024.02.009
  • Title: Transferrin Is Up-Regulated by Microbes and Acts as a Negative Regulator of Immunity to Induce Intestinal Immunotolerance
    Authors: Tang X, Fang M, Cheng R, Niu J, Huang X, Xu K, Wang G, Sun Y, Liao Z, Zhang Z et al.
    Journal: Research (Washington, D.C.)
    Date: January 2024
    DOI: 10.34133/research.0301
  • Title: Lipopolysaccharide-Binding Protein Expression is Increased by Stress and Inhibits Monoamine Synthesis to Promote Depressive Symptoms
    Authors: Fang M, Li Y, Liao Z, Wang G, Cao Q, Li Y, Duan Y, Han Y, Deng X, Wu F et al.
    Journal: Immunity
    Date: February 2023
    DOI: 10.1016/j.immuni.2023.02.002
  • Title: An Undefined Cystatin CsCPI1 from Tea Plant Camellia sinensis Harbors Antithrombotic Activity
    Authors: Fang M, Cha JH, Wang HC, Ye P, Chen B, Chen M, Yang WH, Yan X
    Journal: Biomedicine & Pharmacotherapy
    Date: January 2023
    DOI: 10.1016/j.biopha.2023.114285
  • Title: Hypoxia and Low Temperature Upregulate Transferrin to Induce Hypercoagulability at High Altitude
    Authors: Li M, Tang X, Liao Z, Shen C, Cheng R, Fang M, Wang G, Li Y, Tang S, Xie L et al.
    Journal: Blood
    Date: November 2022
    DOI: 10.1182/blood.2022016410