ACTREC,TMC - India

Author Profile 

ORCID

🧪 Early academic pursuits

Chaudhary s. nazia's academic journey began with an intense passion for microbiology, which led her to achieve a stellar 80% in her bachelor’s degree from sophia college, university of mumbai, in 2013. she further pursued a master’s degree in microbiology at st. xavier’s college, where she graduated with distinction, securing 73.5% in 2015. her academic foundation set the stage for a doctoral pursuit at the advanced centre for treatment, research, and education in cancer (actrec), where she completed her phd in march 2022. her research explored the intricate mechanisms that promote tumorigenesis and resistance to radio- and chemotherapy.

🧬 Professional endeavors

Nazia embarked on a remarkable career as a dst inspire faculty at actrec-tata memorial centre (tmc). her dedication to understanding cancer biology has been a cornerstone of her professional work. through rigorous experimentation and innovative approaches, she has consistently contributed to advancing research in oncology. her faculty position at actrec underscores her commitment to fostering new scientific breakthroughs and mentoring future researchers in the field.

🔬 Contributions and research focus

Nazia’s research revolves around understanding cancer mechanisms at the molecular level. her phd project provided groundbreaking insights into the pathways that promote tumorigenesis and resistance to treatment in the absence of plakophilin 3. her earlier work includes projects on thermophiles from ganeshpuri hot springs, Cancer research- therapy resistance mitochondrial function regulation, and industrially important thermophilic actinomycetes. her innovative studies highlight her ability to blend fundamental microbiological concepts with cutting-edge biomedical applications.

🏆 Accolades and recognition

Nazia’s groundbreaking research has been recognized through prestigious patents. she is a co-inventor of two patents focused on antibodies against lipocalin-2 and Cancer research- therapy resistance their therapeutic applications. these patents signify her impactful contributions to cancer treatment strategies and her recognition as a key innovator in her field.

🌍 Impact and influence

Nazia’s work has influenced the scientific community by providing deeper insights into tumor biology and therapeutic resistance. her contributions to understanding Cancer research- therapy resistance mitochondrial regulation and cancer pathways have added valuable knowledge to the field of molecular oncology. as a dst inspire faculty, she continues to inspire and guide young researchers, amplifying her influence in shaping the next generation of scientists.

🌟 Legacy and future contributions

With her focus on uncovering novel therapeutic targets and mechanisms in oncology, nazia aims to create a legacy of impactful research that bridges fundamental science and clinical applications. her continued efforts in cancer research promise to deliver innovative solutions that could transform patient care and improve outcomes for those affected by the disease. her dedication to mentorship ensures her knowledge and passion will resonate through the researchers she inspires.

Notable Publications 

  • Title: LCN2 promotes focal adhesion formation and invasion by stimulating Src activation
    Author(s): Bhagya Shree Choudhary; Nazia Chaudhary; Aditi Vijan; Dibita Mandal; Leena Pilankar; Shubham Gawand; Bushra K. Khan; Anusha Shivashankar; Rinki Doloi; Neha Joshi et al.
    Journal: Preprint
  • Title: EGFR-to-Src family tyrosine kinase switching in proliferating-DTP TNBC cells creates a hyperphosphorylation-dependent vulnerability to EGFR TKI
    Author(s): Nazia Chaudhary; Bhagya Shree Choudhary; Anusha Shivashankar; Subhakankha Manna; Khyati Ved; Shagufa Shaikh; Sonal Khanna; Jeetnet Barr; Jagruti Dani; Nandini Verma
    Journal: Preprint
  • Title: GPX4-VIM equates a proliferating DTP state in TNBC subtypes with converged vulnerabilities to autophagy and glutathione inhibition
    Author(s): Nazia Chaudhary; Bhagya Shree Choudhary; Sushmita Patra; Shivani Malvankar; Anusha Shivashankar; Eeshrita Jog; Vaishali V. Kailje; Sonal Khanna; Subhakankha Manna; Sarthak Sahoo et al.
    Journal: Preprint
  • Title: Lipocalin 2 inhibits actin glutathionylation to promote invasion and migration
    Author(s): Choudhary BS; Chaudhary N; Shah M; Dwivedi N; P K S; Das M; Dalal SN
    Journal: FEBS Letters
  • Title: The Role of Lipocalin 2 (LCN2) in Regulating Ferroptosis and Therapy Resistance
    Author(s): Rinki Doloi; Nazia Chaudhary; Sorab N. Dalal
    Journal: National Research Scholars' Meet 2021 - Abstracts
Dr. Nazia Chaudhary -Cancer research- therapy resistance – Best Researcher Award